What is Forensic Toxicology?
Forensic toxicology is a specialized scientific discipline that examines drugs (including alcohol), poisons, and their harmful effects on the human body, with particular focus on interpreting these findings for legal proceedings. This field plays a crucial role in both criminal investigations and civil litigation, providing scientifically validated evidence about substance-related impairment or poisoning.
The practice of forensic toxicology primarily divides into two key areas of analysis: antemortem (involving living individuals) and postmortem (involving deceased persons). Each serves distinct but equally vital functions in legal investigations and public safety.
Antemortem toxicology typically deals with cases where substance impairment is suspected in living individuals. Common scenarios include:
- Law enforcement investigations of impaired driving, where breath alcohol analysis provides immediate evidence
- Workplace incidents where oral fluid, blood, and/or urine samples can reveal substance use that may have contributed to accidents
- Criminal cases assessing whether a suspect was under the influence during an alleged offense
These analyses help determine if and how substances affected an individual’s behavior or cognitive abilities at specific times, which becomes critical evidence in legal proceedings.
How Forensic Toxicology Solves Complex Death Cases
Postmortem toxicology serves as an essential tool for medical examiners and coroners. In death investigations, forensic toxicologists analyze samples such as:
- Femoral blood, which offers the most reliable postmortem substance concentration
- Urine, which can reveal longer-term substance use patterns
- Vitreous humor from the eyes, which resists decomposition better than other fluids
Such examinations prove invaluable in various death scenarios:
- Homicide investigations where substance influence may explain victim or perpetrator behavior
- Accidental deaths from falls, drownings, or fires where impairment could be a contributing factor
- Suspected poisoning cases where toxicology can confirm or rule out fatal intoxication
The work of forensic toxicologists like Jim Wigmore bridges the gap between complex scientific analysis and practical legal applications. Their expertise helps answer critical questions about substance effects, timing of exposure, and degree of impairment – all of which can profoundly impact legal outcomes and public safety policies.
By applying rigorous scientific methods to real-world cases, forensic toxicology provides objective evidence that stands up to courtroom scrutiny while advancing our understanding of substance-related risks in society.

Forensic toxicology provides factual data on the influence of toxic substances on a person’s behaviour and contributes to a narrative needed by the judicial system to make appropriate decisions.
